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Por Gabriella Ramos, Paulo Gon�alves, EPTV e cassino roleta brasil Campinas e Regi�o
14/12/2023 05h03 Atualizado 14/12/2023
Pesquisa da Unicamp?? mostra que propriedade do maracuj� pode prevenir c�ncer de pr�stata
Frequentemente descartado, o baga�o de maracuj� � fonte de um extrato?? que pode se tornar aliado na luta contra o c�ncer de pr�stata. � o que indica uma tese de doutorado?? desenvolvida por meio de uma parceria entre dois institutos da Universidade de Campinas (Unicamp).
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Segundo M�rio Roberto Mar�stica J�nior, professor e coorientador do estudo, a etapa pr�-cl�nica indicou que o composto extra�do da?? fruta conseguiu retardar o desenvolvimento dos tumores em experimentos feitos em camundongos, revelando ser um alimento com potencial de preven��o.
�Trabalhamos?? sempre com os alimentos no campo da preven��o, n�o da cura. N�o posso dizer que isso vai servir para curar?? a doen�a em um ano. � importante manter os p�s no ch�o e entender que descobrimos mecanismos que explicam a?? a��o do maracuj� contra o desenvolvimento do c�ncer de pr�stata como um potencial aliado para a utiliza��o dele na preven��o�,?? destaca Mar�stica.
?? Nesta reportagem voc� vai ver:
Como foi feito o estudo?Qual � a rela��o entre maracuj� e c�ncer de pr�stata?Quais?? s�o os pr�ximos passos?
Polpa de maracuj� � 
: Pedro Santana/EPTV
Como foi feito o estudo?
Para entender como as propriedades da fruta?? agem no corpo, os pesquisadores utilizaram um extrato do baga�o desenvolvido anteriormente pelo professor Julian Martinez e patenteado pela universidade.?? Com a subst�ncia em m�os, era hora de entender a a��o biol�gica do composto.
�Estudamos o ponto de vista da redu��o?? da probabilidade de incid�ncia da doen�a, e isso foi o que a gente fez no modelo de c�ncer de pr�stata.?? Por que o c�ncer de pr�stata? Porque � o mais incidente para o p�blico masculino e, se for descoberto logo,?? tem maior possibilidade de revers�o�, explica.
O experimento utilizou camundongos que desenvolvem, de maneira progressiva, les�es na pr�stata que imitam o?? c�ncer em humanos. Os animais receberam o composto de maracuj� por cerca de 2 a 3 meses, per�odo no qual?? foi poss�vel observar a redu��o dos tumores.
Maracuj� e c�ncer de pr�stata
Mar�stica explica que o maracuj� foi escolhido por possuir compostos?? fen�licos, tamb�m conhecidos como antioxidantes. �Eles revertem, por exemplo, radicais livres. Eles impedem que esses radicais livres se propaguem e?? que eles ajam�, explica o professor.
Os radicais livres, porcassino roleta brasilvez, t�m um papel importante no in�cio do c�ncer: quando?? os radicais livres est�o presentes em excesso no organismo, as c�lulas come�am a crescer desordenadamente e levam ao aparecimento de?? doen�as cr�nicas e n�o transmiss�veis, relacionadas ao estilo de vida.
"O estilo de vida � um fator preponderante. Quando a gente?? insere um alimento ou um extrato, por exemplo, que � rico nesses compostos antioxidantes, ele atua para reverter esses processos?? que levam, em tese, ao desenvolvimento da doen�a. Ent�o, eles acabam sendo protetores", afirma.
Al�m disso, a pesquisa identificou que o?? extrato do baga�o do maracuj� tamb�m reduziu o processo de angiog�nese - em outras palavras, o crescimento de novos vasos?? sangu�neos. �Quanto mais vascularizado for o tumor, mais ele vai crescer. Ou seja, tem sangue chegando ali, ent�o tem nutriente?? e vai crescendo. Se voc� diminui essa angiog�nese, voc� diminui o crescimento do tumor�.
Os pesquisadores tamb�m notaram o efeito da?? subst�ncia na apoptose, ou morte das c�lulas. �Toda c�lula nasce e morre, s� que a c�lula cancer�gena perde essa capacidade.?? Esse extrato aumentou a porcentagem de apoptose, que � a morte dessa c�lula cancer�gena�, destaca Mar�stica.
Professor M�rio Roberto Mar�stica J�nior,?? da Faculdade de Engenharia de Alimentos da Unicamp � 
: Pedro Amatuzzi/Inova Unicamp
Quais s�o os pr�ximos passos?
O coorientador do estudo?? frisa que, atualmente, n�o h� testes em humanos em andamento, e eventuais estudos com pacientes diagnosticados com c�ncer de pr�stata?? requerem cuidado porque envolvem diversas vari�veis e quest�es �ticas.
Para o futuro, uma possibilidade seria o desenvolvimento de um nutrac�utico �?? tamb�m definido como uma categoria de suplemento alimentar feita a partir de alimentos que t�m compostos ben�ficos para a sa�de?? � � base do extrato.
LEIA TAMB�M:
Como produto � base de urucum criado com tecnologia da Unicamp pode combater gordura no?? f�gado
Outra esperan�a � o est�mulo do uso de subprodutos da ind�stria, como o baga�o do maracuj�, para produ��o de compostos?? de alto valor agregado. �Caminhar nessa dire��o da preserva��o da biodiversidade, est�mulo do consumo e est�mulo do aproveitamento global dos?? alimentos pela ind�stria�, diz o professor.
V�DEOS: tudo sobre Campinas e regi�o
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